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Pipeline

We are building a diverse pipeline of novel immunometabolic modulators.

At the core of our discovery engine lies a “specialized” library of small molecules uniquely designed to engage with lipid-binding proteins. Our profound understanding of lipid biology and the mechanisms by which our specialized drugs interacts with their target proteins to modulate immune cell metabolism guide our development efforts.

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  Discovery: Identify lead compounds that selectively engage with the biological target and influence its function in cells

  In vivo proof-of concept (POC): Establish disease modifying activity of the drug candidates in relevant animal models

  Lead optimization: Optimize efficacy, pharmacokinetic and toxicokinetic parameters

  Investigational new drug (IND)-enabling: Perform studies required by the regulator authorities for initiating human clinical trials

 

*In combination with immunotherapy

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